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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
Recording available 2/16-5/2
Recording available 2/16-5/2
AIUM Credit
AIUM Credit
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Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 1

Category: Clinical Obstetrics

Poster Session 1

(281) Use of Multiple Substances in a Pregnant Population with Substance Use Disorder

Wednesday, February 11, 2026
10:30 AM - 12:00 PM  

    Submitting Author and Presenting Author(s)

  • Macy Afsari, BS (she/her/hers)

    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

    • Coauthor(s)

  • Allison Kurzeja, MD (she/her/hers)

    MFM Fellow
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • MF

    Mary Ann Faucher, CNM, MPH, PhD

    Parkland Health
    Lubbock, Texas, United States

  • PC

    Polly B. Cordova, CNM, DNP

    Certified Nurse Midwife, Integrated Family Planning Opioid Project
    Parkland Health
    Dallas, Texas, United States

  • JM

    Jessica McNeil, CNM, DNP

    Certified Nurse Midwife, Integrated Family Planning Opioid Project
    Parkland Health
    Dallas, Texas, United States

  • AF

    Amber Fisher

    Parkland Health
    Dallas, Texas, United States

  • SM

    Stephanie Morillos

    Parkland Health
    Dallas, Texas, United States

  • JK

    Joshua Kern, MD

    Assistant Professor, Department of Emergency Medicine
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • NO

    Nancy S. Onisko, DO

    Assistant Professor of Emergency Medicine; Assistant Director of the Perinatal Intervention Program
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • AA

    Aldo Andino, MD

    Assistant Professor of Emergency Medicine
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • KK

    Kurt Kleinschmidt, MD

    Professor of Emergency Medicine, Director of Perinatal Intervention Program
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • AG

    April R. Gorman, MS

    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

  • Emily H. Adhikari, MD (she/her/hers)

    Associate Professor
    University of Texas Southwestern Medical Center
    Dallas, Texas, United States

Objective:
Use of multiple substances significantly increases the risk for overdose-related death. Data on trends in substance use combinations among pregnant individuals is limited. The objective of this study was to describe patterns of use of multiple substances in a pregnant population in an urban setting.

Study Design:
This was a retrospective cohort study of pregnant patients with moderate to severe substance use disorder (SUD) who received care at a safety-net hospital. Substance use patterns were obtained via medical record review, including patient-reported use patterns and urine toxicology screens. A correlation matrix was generated to describe strength of association for each pair of substances with R-factor >|0.7| considered strong association.

Results:

From July 28, 2021 through June 25, 2022, 184 patients with SUD were identified. Eighty-five (46%) patients identified as Hispanic, 65(35%) identified as Non-Hispanic White, 32(17%) as Non-Hispanic Black, and 2(1%) as Asian. Of these, 177(64%) attended prenatal care. Forty-five (24%) patients reported use of only one substance. Of those with use of only one substance, 17(38%) used opiates, 13(29%) used alcohol, 10(22%) used methamphetamine, 3(7%) used prescription stimulants, and 2(4%) used cocaine. Among the remaining 139(76%) patients with use of multiple substances, there was a strong negative correlation between use of stimulants and cocaine together (R-factor -0.99) and benzodiazepines and hallucinogens together (R-factor -0.93). There were moderate positive correlations between use of hallucinogens and cocaine (R-factor 0.54), stimulants and hallucinogens (R-factor 0.46), and benzodiazepines and stimulants (R-factor 0.42).

Conclusion:
This study provides valuable insight into the complex patterns of substance use in pregnant patients with known SUD, with a majority engaging in use of multiple substances. These findings reflect the need for ongoing comprehensive screening and interventions to address multiple substance use in this population. Further research is essential to validate these patterns and link them to maternal and neonatal outcomes.