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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
Recording available 2/16-5/2
Recording available 2/16-5/2
AIUM Credit
AIUM Credit
Foundation Awardee
Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 3

Category: Epidemiology

Poster Session 3

(725) Psychosocial stressors and 30 year cardiovascular risk score for individuals with obstetric risk factors

Thursday, February 12, 2026
10:30 AM - 12:00 PM  
Objective:
Obstetric (OB) risk factors including prior preterm birth and hypertension are linked to increased cardiovascular (CVD) risk, but it is unclear if stress compounds CVD risk associated with OB risk factors. We examined associations between psychosocial stress and projected 30‑year CVD risk for individuals with high and low OB risk.

Study Design:
The prospective Stress, Pregnancy, and Health study collected stress measures during 2nd and 3rd trimesters and documented clinical outcomes for 605 participants 2018-2023. High OB risk was defined by history of IUGR, preterm birth < 37wks, PPROM, or IUFD in a prior pregnancy, or current or prior hypertensive disorder in the prior or index pregnancy. Food insecurity, loneliness, financial hardship, and depressive symptoms were calculated from validated questionnaires. PREVENT 30‑year CVD risk score (percent probability of a first CVD event within 30yrs) was calculated with the AHA equation that uses age, systolic blood pressure, non-HDL cholesterol, diabetes, smoking, and estimated glomerular filtration rate. Stress and PREVENT scores were z‑scored for comparability. Linear regressions within each OB‑risk group were adjusted for race/ethnicity and education/occupation.

Results:
Among 469 participants, the high OB risk group (n=148) had a higher proportion of Black participants (25.7 vs. 14.6%) and lower socioeconomic status. Mean PREVENT scores were significantly higher in the high-risk group (0.40 ± 1.46 vs –0.18 ± 0.62). Within the high‑risk group, a 1‑SD increase in loneliness (β=0.23, 0.003–0.45) and depressive symptoms (β=0.23, 0.01–0.46) were significantly associated with corresponding increases in PREVENT scores. Food insecurity trended toward higher PREVENT scores (β=0.19, -0.03–0.40). In the low‑risk group (n=321), no stressors were associated with CVD risk score.

Conclusion:
Loneliness and depressive symptoms were associated with increase in 30‑year CVD risk in high‑OB‑risk pregnancies. Psychosocial screening in prenatal care may identify opportunities to reduce long-term health risk, particularly for individuals with obstetric risk factors.