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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
Recording available 2/16-5/2
Recording available 2/16-5/2
AIUM Credit
AIUM Credit
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Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 3

Category: Clinical Obstetrics

Poster Session 3

(728) Risk factors and perinatal outcomes in patients with placenta previa delivered for severe antepartum bleeding

Thursday, February 12, 2026
10:30 AM - 12:00 PM  
Objective:
Data on risk factors associated with delivery for severe bleeding and perinatal outcomes in patients with placenta previa remains lacking. We investigated potential risk factors associated with need for delivery due to severe bleeding and related perinatal outcomes.

Study Design:
Retrospective cohort study of pregnant patients with ultrasound-confirmed placenta previa, delivered at a single tertiary health system from 6/2013-3/2025. Resolved previa or low-lying placenta were excluded. Primary outcome was risk factors associated with delivery for severe bleeding. Secondary analysis of obstetric and neonatal outcomes also conducted. Obstetric outcomes included composite of cesarean hysterectomy, ICU admission, postpartum hemorrhage (PPH), and blood transfusion, EBL >1.5 and 2L, and preterm birth. Neonatal outcomes included composite of mechanical ventilation, respiratory distress syndrome (RDS), sepsis, seizure, intraventricular hemorrhage (IVH), and neonatal death, NICU admission and length of stay. Bivariate statistics used to analyze data. Regression models used to control for confounders.

Results:
Of 247 included patients, 79 (32%) were delivered for severe bleeding. Demographics and clinical characteristics were similar between cohorts. No individual factors were identified to be independently associated with an increased risk of delivery for severe bleeding (Table 1). However, after controlling for confounders, those delivered for severe bleeding had higher odds of adverse composite delivery outcome, PPH, EBL >1.5 and >2L, blood transfusion, and preterm birth (Table 2). No significant differences seen in neonatal outcomes (Table 2).

Conclusion:
No independent risk factors associated with delivery for refractory bleeding were identified. Patients delivered for refractory bleeding had significantly higher odds of adverse maternal and delivery outcomes without differences in neonatal outcomes.