(367) Determinants of COVID-19 Vaccine Uptake Among Low-Income, Latinx Pregnant Individuals in California’s San Joaquin Valley

To investigate the association between COVID-19 vaccination uptake and demographic, socioeconomic, and clinical factors among low-income pregnant and postpartum individuals in California’s San Joaquin Valley.

Study Design:
This is a secondary analysis of data collected as part of the EMBRACE study, a randomized trial comparing the effectiveness of two enhanced prenatal care models. Participants were low-income pregnant individuals, 72% of whom identified as Latinx. We conducted bivariate analyses and a stepwise logistic regression to determine the association between participant characteristics and COVID-19 vaccine uptake. Covariates included age, ethnicity, birthplace, language of interviews, educational attainment, monthly household income, relationship status, parity, and diagnosis of mental health condition.

Results:
Among the 652 study participants, 61.5% reported having received a COVID-19 vaccine. 45.7% were vaccinated before pregnancy, 9.6% during pregnancy, and 6.1% after giving birth. In the stepwise multivariable logistic regression model, older age was associated with higher odds of being vaccinated (OR = 1.09, 95% CI: 1.04–1.14, p < 0.001). Participants with one to two children had significantly lower odds of vaccination compared to those without children (OR = 0.34, 95% CI: 0.20–0.56, p < 0.001), as did those with three or more children (OR = 0.27, 95% CI: 0.13–0.55, p < 0.001).

Conclusion:
Age and parity are associated with COVID-19 vaccination uptake in this population. Older individuals were more likely to be vaccinated. However, individuals with children had significantly lower odds of vaccine uptake, suggesting the need to explore caregiving-related barriers. We should consider outreach strategies to improve vaccination access and acceptance among younger people and parents.