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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
Recording available 2/16-5/2
Recording available 2/16-5/2
AIUM Credit
AIUM Credit
Foundation Awardee
Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 1

Category: Hypertension

Poster Session 1

(100) Time interval from diagnosis to delivery in patients with early-onset preeclampsia with severe features

Wednesday, February 11, 2026
10:30 AM - 12:00 PM  
Objective:
To evaluate characteristics associated with delivery ≤7 days after diagnosis in patients with early-onset preeclampsia with severe features (EoPE with SF) to inform timing of ACS administration.

Study Design:
Multicenter retrospective cohort study including all patients diagnosed with EoPE with SF between 23 0/7-33 6/7 weeks from 1/1/2018-12/31/2023. Patients with postpartum diagnosis, intrauterine fetal demise, preterm prelabor rupture of membranes, missing data, or declined recommended delivery were excluded. Cases were stratified into two groups based on time interval from diagnosis to delivery: ≤7 versus > 7 days. Multivariable logistic regression was performed to evaluate associations between patient characteristics, comorbidities, and clinical presentation with delivery ≤7 days. Data are presented as adjusted odds ratios (aOR) with 95% confidence intervals (CI).

Results:
Of the 249 patients included, 180 (72.3%) delivered < 7 days after diagnosis. Patient characteristics, comorbidities, and clinical presentation data compared between the two groups are displayed in Table 1. Among patients who were diagnosed with EoPE with SF based on severe hypertension alone (n=176), hypertension with additional symptoms (n=47), and hypertension with abnormal lab evaluation (n=23), the rates of delivery < 7 days were 65.9%, 89.3%, and 82.6%, respectively. Patients diagnosed based on hypertension and additional symptoms, as well as those presenting with proteinuria had higher odds of delivery < 7 days (aOR 4.57, 95% CI 1.39-14.97, and 2.06, 95% CI 1.04-4.07, respectively) (Table).

Conclusion:
Most patients diagnosed with EoPE with SF deliver < 7 days after diagnosis, with diagnosis by severe hypertension with symptoms and presenting with proteinuria being associated with higher odds of delivery < 7 days. The likelihood of delivery < 7 days after diagnosis remained >65% regardless of the criteria for diagnosis or clinical presentation at the time of diagnosis. Therefore, ACS administration should not be delayed in this population.