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CME Credit Offered
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Recording available 2/16-5/2
Recording available 2/16-5/2
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AIUM Credit
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Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 2

Category: Diabetes

Poster Session 2

(606) Not All Single OGTT Abnormalities Are Equal: Fasting Abnormal value is correlated with GDMA2

Wednesday, February 11, 2026
3:30 PM - 5:00 PM  
Objective:
An isolated abnormal value on the Oral Glucose Tolerance Test (OGTT) is associated with complications similar to those of gestational diabetes mellitus and is often treated the same way. In this study, we aimed to identify which of the four specific tests evaluated in the OGTT is most closely correlated with the requirement for pharmacologic treatment in gestational diabetes (GDMA2).

Study Design:
This retrospective cohort study included women with one pathological value in OGTT over 8 years. Participants were divided into four groups based on which one of the OGTT measurements was elevated: fasting (0h), 1-hour, 2-hour, or 3-hour. Obstetric and neonatal outcomes were compared across groups. Multivariable logistic regression was performed to assess associations, adjusting for potential confounding variables.

Results:

A total of 671 women were included: Elevated fasting glucose values were found in 176 women, an increased value at one hour in 364 women, two hours in 112 women, and three hours in 19 women. The highest proportion of GDMA2 was observed among women with isolated abnormal fasting glucose (51%), whereas the rates of GDMA2 were significantly lower among those with isolated post-load abnormalities at 1-hour (17%), 2-hour (19%), and 3-hour (16%) (p < 0.001). Multivariable logistic regression analysis demonstrated that fasting elevated glucose had the strongest association with GDMA2 compared to post-load abnormalities. Women with elevated values at 1-hour (aOR 0.22, 95% CI 0.15–0.33, p < 0.001), 2-hour (aOR 0.22, 95% CI 0.12–0.39, p < 0.001), and 3-hour (aOR 0.17, 95% CI 0.04–0.55, p = 0.007) were significantly less likely to require pharmacologic treatment.  

Conclusion:

Among women with a single abnormal OGTT value, a fasting abnormality is associated with a significantly higher risk of GDMA2. These findings suggest that the specific abnormal test in OGTT has predictive potential for the severity of gestational diabetes mellitus.