Poster Session 3
Category: Clinical Obstetrics
Poster Session 3
Amir Snir, MD
Soroka University Medical Center
omer, HaDarom, Israel
Tamar Wainstock, PhD (she/her/hers)
Department of Epidemiology, Biostatistics and Community Health Sciences, Faculty of Health Sciences, Ben-Gurion University of the Negev
Beer Sheva, HaDarom, Israel
Eyal Sheiner, MD, PhD
Deichmann Lerner Full Professor of Obstetrics & Gynecology; Chairman of the Division of OBY&GYN
Soroka University Medical Center, Faculty of Health Sciences, Ben‑Gurion University of the Negev
beer sheva, HaDarom, Israel
Symphysiolysis is a bothering complication in pregnancy. The severity of symptoms varies from mild discomfort to severely debilitating pain. In this study we aimed to investigate whether beyond the discomfort, documented symphysiolysis is associated with adverse perinatal outcomes and whether it constitutes as an independent risk factor for cesarean delivery (CD) and labor induction.
Study Design:
A population-based cohort study was performed in a tertiary medical center including all singleton deliveries born between the years 1991-2021. Adverse perinatal outcomes were compared between pregnancies of women with and without documented symphysiolysis. The diagnoses were defined based on ICD-9 codes as recorded in the hospital medical files. Multiple logistic regression models were used to control for confounders.
Results:
Out of 232,476 patients, 227 (0.1%) were diagnosed with symphysiolysis during pregnancy. Perinatal outcomes such as low Apgar (< 7) at 5 minutes (OR= 0.7, 95% CI 0.1 - 5.1, p=0.739) and perinatal mortality (OR=0.54, 95% CI 0.07 – 3.8, p=0.53) were comparable between the groups. Higher rates of labor induction (OR 2.0, 95% CI 1.5 - 2. 7, p < 0.001) and CD (OR=4.3, 95% CI 3.3 - 5.65, p < 0.001, Table) were noted in pregnancies complicated by symphysiolysis. Using multiple logistic regression models, controlling for confounders such as maternal age, gestational diabetes mellitus, smoking, fertility treatments and mild pre-eclampsia, symphysiolysis was noted as an independent risk factor for labor induction (adjusted OR= 1.8, 95% CI 1.3 – 2.4; p < 0.001) and CD (adjusted OR= 2.3, 95% CI 1.9-2.9; p < 0.001).
Conclusion:
Symphysiolysis is an independent risk factor for cesarean delivery and labor induction. However, it is not associated with adverse perinatal outcomes.