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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
Recording available 2/16-5/2
Recording available 2/16-5/2
AIUM Credit
AIUM Credit
Foundation Awardee
Foundation Awardee
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Abstract Award
Abstract Award
Foundation Awardee
Foundation Awardee

Poster Session 2

Category: Ultrasound/Imaging

Poster Session 2

(503) Routine Comprehensive First Trimester Anatomy Scans: Enhanced Early Detection of Fetal Anomalies

Wednesday, February 11, 2026
3:30 PM - 5:00 PM  
Objective:
The sonographic midsagittal fetal view traditionally used for nuchal translucency (NT) measurements provides limited anatomical information. Although SMFM and AIUM endorse targeted early anatomy assessments, neither mandates comprehensive first trimester fetal evaluations. This study assesses the added diagnostic value of routine comprehensive first trimester anatomy scans compared to standard NT scans for early detection of fetal anomalies.

Study Design:
In June 2024, our institution adopted a protocol to routinely perform comprehensive first trimester fetal anatomy scans (including NT measurements) between 12 and 13 weeks and 6 days gestation, replacing traditional midsagittal NT sonograms. This retrospective cohort study compares patients who underwent standard NT scans (N=11,010, June 2023–May 2024) with those who received comprehensive first trimester anatomy scans (N=10,954, June 2024–June 2025). Data were extracted from a dedicated ultrasound registry. Scans were classified as abnormal if the NT thickness was >3 mm, structural anomalies were identified, or both. The primary outcome was abnormal scan frequency; secondary outcomes included detection rates of specific anomalies by organ system.

Results:
Abnormal scans were reported in 0.87% of standard NT scans versus 0.76% of comprehensive first trimester anatomy scans (p=0.34). The standard NT scan showed significantly higher detection of NT-related abnormalities (increased NT/cystic hygroma; 0.84% vs. 0.36%; p< 0.007). Conversely, the comprehensive first trimester anatomy scan identified significantly more structural anomalies in craniofacial (0.17% vs. 0.07%; p=0.036), cardiac (0.24% vs. 0.09%; p=0.030), abdominal (0.23% vs. 0.10%; p=0.048), renal (0.08% vs. 0.00%; p=0.018), and spinal (0.07% vs. 0.00%; p=0.021) systems. 

Conclusion:
Routine comprehensive first trimester anatomy scans significantly enhance early detection of structural fetal anomalies compared to standard midsagittal NT scans, facilitating earlier counseling and diagnostic testing. We recommend comprehensive first trimester anatomy screening for all pregnant women.