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Poster Session 3

Category: Medical/Surgical/Diseases/Complications

Poster Session 3

(704) Correlation of Point-of-Care Viscoelastic Testing and Standard Indices in an Obstetric Population

Thursday, February 12, 2026

10:30 AM - 12:00 PM

Submitting Author and Presenting Author(s)

Alesha M. White, MD (she/her/hers)

Maternal Fetal Medicine Fellow
University of Texas Southwestern Medical Center
Grand Prairie, Texas, United States

Coauthor(s)

DM

Donald D. McIntire, PhD

University of Texas Southwestern Medical Center
Dallas, Texas, United States
WT

Weike Tao, MD

University of Texas Southwestern Medical Center
Dallas, Texas, United States
BA

Brenda Anyaehie, MD

University of Texas Southwestern Medical Center
Dallas, Texas, United States
SY

Sean Yates, MD

University of Texas Southwestern Medical Center
Dallas, Texas, United States
David B. Nelson, MD (he/him/his)

Associate Professor and Division Chief
University of Texas Southwestern Medical Center
Dallas, Texas, United States

Objective:
As coagulopathy is a major possible complication of postpartum hemorrhage (PPH), use of coagulation labs are recommended to guide transfusion. The use of viscoelastic point-of-care tests (POC) has not been validated in the setting of PPH but has been shown to help in the guidance of transfusion in other areas of medicine. The objective of this study was to demonstrate the correlation of standard coagulation labs with two different viscoelastic tests.

Study Design:
This is a prospective observational study of patients who experienced PPH or who were at risk of experiencing PPH at the time of delivery. This data is a subgroup from a single-center within a larger, multicenter industry sponsored study to validate a POC viscoelastic assay device, the Quantra® sonorheometry (SEER) system. The correlation of hematologic indices with rotational thromboelastometry (ROTEM) and Quantra as well as the correlation of ROTEM with POC Quantra were compared with P< 0.05 considered significant.

Results:
Of the total 40 samples, ROTEM assays were collected for 18 (45%) of patients and Quantra assays were collected for 40 (100%) patients. Conventional coagulation labs had a high correlation coefficient when compared to their ROTEM and Quantra equivalents, approaching 0.7 in all lab indices (all p< 0.05). Additionally, ROTEM and Quantra correlated well amongst themselves in the two examined equivalent parameters with correlation coefficients greater than 0.9 (all p< 0.05). Notably, the median total time for final result of Quantra was significantly less than ROTEM (p< 0.001) with Quantra having a first report projection of 2.2 [2.05,2.28] minutes.

Conclusion:
Overall, the coagulation labs examined here correlate well with ROTEM and Quantra. POC Quantra results returned at significantly faster times compared to ROTEM. Further randomized controlled trials are needed to examine the impact of POC devices such as Quantra on guidance of transfusion in the setting of PPH.